ReceptIVFity

ReceptIVFity

ReceptIVFity is a predictive test for assessing the current suitability of an individual woman’s embryo implantation acceptation, prior to starting an IVF treatment – with or without ICSI – based on vaginal microbiome measurements.

Scientific research has demonstrated that the composition of bacteria in the vagina (the vaginal microbiome) plays an important role in the chances of achieving a successful pregnancy using fertility treatments such as IVF or ICSI. 

Before the start the IVF or ICSI treatment, the patient will collect some mucus from the vagina using a swab from the test pack. After collecting the sample, she will place the cotton swab in the tube with liquid that has been provided and give this tube to the physician. The tube with the sample will then be sent to the laboratory. In the laboratory, the bac­terial DNA collected from this sample will be analyzed – quantitatively and qualitatively – and will de­termine the woman’s individual microbiome profile. The physician can check the result from the lab within 7 working days here and will discuss the results with the patient.

The result

The ReceptIVFity test determines the profile of the bacterial balance in the vagina and can result in an unfavourable, good or very good score.

• One out of 20 women gets an UNFAVOURABLE score; this means the chance of becoming pregnant after an IVF or ICSI treatment is low (5.2%)*.
• On average, 7 out of 20 women get a GOOD score, in which case the chance of pregnancy is 34.4%*.
• On average, 13 out of 20 women get a VERY GOOD score, in which case the chance of pregnancy is high (64.6%)*.

*% of confirmed pregnancies by ultrasound after first embryo transfer following sampling

Decision making process

When a patient has a high ReceptIVFity score, this does not mean that she will definitely become pregnant, but the chances are good. On average, the first IVF or ICSI treatment has just over 30% chance of resulting in a pregnancy and a high score profile increases this chance to 50%.

If the test results in a low score, the patient can consult her doctor about the options. It is important to realise that the proven reliability of the test is for a limited period of maximum two months following the test. The bacterial profile can change over time. After consulting the doctor, and based on the patient’s personal circumstances, she decides whether or not to start IVF or ICSI treatment at that time.

Being able to assess a low chance situation, ReceptIVFity enables doctors and patients to optimize the timing of IVF-treatments. The test also helps to reduce patients’ uncertainty and stress by disclosing more knowledge upfront.