Research & Development
Pilot Shared Decision Making
We are currently running a pilot in Erasmus MC. This is a collaboration with Erasmus MC and CZ healthcare insurer. During the pilot 1000 patients starting an IVF cycle, are offered the ReceptIVFity test. Goal is to study the influence of the test (i.e. having insight in chances of succesful implantation) on the shared decision making process.
The MURIM study (MUltidisciplinary Research on Implantation failure and repeated Miscarriages) studies the differences in the womb lining of women with implantation failure and women with repeated miscarriages. We suspect that there is no successful implantation in both patient groups due to an imbalance in the receptivity and selectivity of an embryo. The womb lining is reviewed on various aspects. The microbiome is tested using the ReceptIVFity test, and the hormonal profile and immune cells are being mapped. In addition, we examine how these different profiles relate to each other.
UNIKid Stability Study
Two German clinics, Universitatsklinikum Dusseldorf and Fertility Center Berlin are collaborating in a stability study of the vaginal microbiome. The ReceptIVFity test is used to look at the stability of the microbiome in a 4 month period. We suspect that the microbiome resulting in a high profile is most stable and a ‘low’profile will be most likely to change over time.
IUI-Trial VivaNeo Leiderdorp
Met VivaNeo Leiderdorp wordt een studie opgezet waar na intra-uterine inseminatie (vaak een stap voor IVF) wordt gekeken en dan m.n. bij lesbienne paren (dan is ook interessant wie volgens onze test de meest geschikte ‘ontvang-moeder’ is). >> tekst nog niet ontvangen
(planned to start 2019)
Two trials at Zealand University Hospital – Denmark
In a prospective cohort study we aim to identify possible endometrial factors as a cause of implantation failure in a group of women with recurrent implantation failure(RIF) and controls. The receptIVFity test covers the role of the vaginal microbiome in both cohorts.
MICrobiome INTervention study (MICINT)
In a randomised double blinded placebo controlled trial we wish to investigate the effect of lactobacilli loaded vaginal supplements on a group of women diagnosed with a low or medium profile using the ReceptIVFity test from ARTPred, and to test the sustainability of the effect over one menstrual cycle.